From Cells to Societies: What do we not know about pain?
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John-Anker Zwart is professor and head of research at the Division of Clinical Neuroscience, Institute of Clinical Medicine, University of Oslo and at Oslo University Hospital. The division of Clinical Neuroscience has been active in patient involvement in research and professional development, at the clinical and project level.
John-Anker Zwart, M.D Ph.D
Ingrid Bånerud works as a research coordinator at the Research Unit for Musculoskeletal Health (FORMI), Division for neuroscience and musculoskeletal medicine at Oslo University Hospital. FORMI has been active in patient involvement in research and professional development, at the clinical and project level. I addition is Ingrid a board member for the Norwegian European Patient Academy for Therapeutic Innovations (EUPATI).
Ingrid Fjeldheim Bånerud, M.S.
Patient representative Norwegian Rheumtatology Association
After living with chronic pain since the age of 17, Anna Fryxelius (44) is an active advocate for patient involvement. She works in the Norwegian Rheumatism Association where she is responsible for organized peer support and patient empowerment programs. Anna lives with Rheumatoid Arthritis and chronic back pain after a complex spinal fracture.
Vesa Kontinen (MD, DMedSci, docent of pharmacology in Univ. of Helsinki and docent of Anesthesiology and Intensive Care Medicine in Univ. of Turku) is an anesthesiologist working as the head of department responsible for the 20 operating theatres at the Jorvi hospital campus, a part of the Helsinki University Hospital. Previously, he has served as the head of the Pain Clinic and in other roles in the Helsinki University Hospital. Earlier he enjoyed life as a basic scientist in pain research in Helsinki under guidance of prof. Eija Kalso, in University College London as a post doc in the lively group of prof. Tony Dickenson, and learning corporate life in Beerse, Belgium with Janssen Pharmaceutica. At present, his research efforts are concentrated in clinical trials and meta-analyses on acute postoperative pain management.
Dr. Christopher Sivert Nielsen is a clinical psychologist and senior researcher at the Department of Chronic Diseases and Aging, Norwegian Institute of Public Health. He also holds positions at the Department of Pain Management and Research, at Oslo University Hospital, and the Department of Community Medicine, at UiT – The Arctic University of Norway. His primary area of interest is in the epidemiology of clinical and experimental pain. He leads the Tromsø Pain Study, which is the largest experimental pain study worldwide, with 10,500 adults examined in 2007-08 and 21,000 examined in 2016-17. The study also includes a cohort of 1,000 adolescents with unique data on social relationships. Major areas of interest include pain genetics and biomarkers, comorbidity between pain and cardiovascular disease, and the influence of social relationships on pain.
Dr. Christopher Sivert Nielsen
Sigridur works as a clinical nurse specialist with the consulting pain team at Landspítali – The National University Hospital of Iceland, and as an Associate Professor at The University of Iceland, Faculty of Nursing. She graduated with BS in nursing 2002, MS in cancer nursing 2008, and received her PhD in 2014 from the University of Iceland, Faculty of Nursing. Her clinical practice includes pain consultations and specialized treatment, training of hospital staff, and building up pain services within the hospital. Her research focuses on symptom assessment and treatment, mainly pain management in the hospital setting. She is the treasurer of the Icelandic Association for the Study of Pain and is the president of the Scandinavian Association for the Study of Pain (SASP).
Sigridur Zoëga, RN, CNS, PhD
Lene Vase received her PhD in experimental psychology in 2006 and she is currently a professor of neuroscience at the Department of Psychology and Behavioural Sciences, School of Business and Social Sciences, Aarhus University, Aarhus, Denmark. Her research focuses on how psychological interventions or dispositions may enhance or decrease the experience of pain with a special focus on placebo analgesia and nocebo hyperalgesia effects. Recently, she has investigated how knowledge of placebo and nocebo mechanisms may improve the test of new treatments in Randomized Controlled Trials. She has published more than 70 papers and book chapters and given several presentations at conferences world-wide. She has numerous international collaborations and she was awarded the EU Innovative Medicines Initiative grant EUROPAIN together with leading pain laboratories in the Europe. She is currently Associate Editor on PAIN and part of the steering committee for the Society for Interdisciplinary Placebo Studies.
Eva Denison is a senior researcher at the Norwegian Institute of Public Health, and adjunct professor in physiotherapy at Mälardalen University, Sweden. She has ten years of experience in conducting systematic reviews, with a main focus on effects of interventions to promote lifestyle changes related to physical activity, diet, smoking, and alcohol use. Her research in physiotherapy concerned integration of a behavioural medicine and physiotherapy approach management of patients with persistent pain. Eva Denison is also involved in teaching evidence-based practice and systematic review methods nationally and internationally.
Carsten Dahl Mørch is an associate professor at the center for neuroplasticity and pain at Aalborg University. Carsten is a basic research and his research relates to the question of how a peripheral stimulus turns into a perception of pain in healthy humans. This involves selective activation of small or large cutaneous nerve fibers using specialized electrodes, laser or contact heat, and assessment of nerve fiber properties. Furthermore, spatiotemporal integration of nociceptive information along the neural-axis appears to shape the perception of pain. Carsten has worked on development and general understanding of some methods to investigate such phenomena in humans.
Carsten Dahl Mørch, M.Sc. Ph.D
•Head of Division for Medical Imaging, Turku University Hospital, and Professor of Clinical neurophysiology, University of Turku, Turku, Finland
•Research: neurophysiology and psychophysics of neuropathic pain, non-invasive therapeutic brain stimulation for pain and tinnitus, PET studies on dopamine-opioid system in pain and analgesia, PET and EEG studies on consciousness, 150 publications (original articles, reviews, textbook chapters), 3 official patents.
•Research Group leader in Turku Brain and Mind Center (TBMC) since 1999 and member of the board of TBMC, University of Turku, 2014-
•Other official and administrative duties: Finnish representative 2012- and secretary 2015- of UEMS section for Clinical neurophysiology; Finnish representative in the IFCN task force group for European core curriculum of specialist training in clinical neurophysiology 2014- ; Member of the IHS working group for revised diagnostic classification of headache disorders (ICHD II) 2010-2013; Member of European panel of experts for Practice Guidelines on therapeutic non-invasive brain stimulation 2012-2014; President and member of the board of the Finnish Society of Clinical Neurophysiology 2010- ; member of the board of the Scandinavian Association for Study of Pain 2005-2011; President of the Brainstem SIG of the International Federation of Clinical Neurophysiology 2018-; Member of the scientific committee of the Finnish Association for the Study of Pain 2008- and president 2014-, Member of the Scientific committee for IASP world congresses 2010, 2012, 2014
•Associate editor in the Editorial board of Pain2009-2014; Associate editor in the Editorial board of Scandinavian Journal of Pain 2009-2011, Member of the Advisory board of Scandinavian Journal of Pain2011-; Section editor of Scandinavian Journal of Pain2015-
•Permanent expert of the Finnish Patient Injuries Board 2009- ; Member of advisory board of Orion Pharma, Research and development unit 2013- ; Member of advisory board of Pfizer, Research and development unit 2014-2016; Member of Expert task force group of Nokia Mobile Phones 1997-2003
Satu K. Jääskeläinen, MD, PhD
Gary Macfarlane is Dean of Research and Knowledge Exchange (Life Sciences and Medicine) at The University of Aberdeen. He has also been Chair in Epidemiology since 2005. He is an Honorary Consultant in Public Health with NHS Grampian. He trained in Statistics/Computing Science and then Medicine at The University of Glasgow before undertaking his PhD on the Epidemiology of Oral Cancer at The University of Bristol. He worked at the Division of Epidemiology and Biostatistics at the European Institute of Oncology in Milan 1991-1995 before leading a programme of chronic pain research at the Arthritis Research UK Epidemiology Unit at the University of Manchester, where he was appointed as chair in 1999. He currently leads the Epidemiology group at the University of Aberdeen which undertakes work on Rheumatic and Musculoskeletal Diseases (RMD). The RMD programme focuses on: mechanistic research, clinical trials and health services research with a clinical focus on musculoskeletal pain and fatigue (including fibromyalgia), spondyloarthritis and rare diseases (vasculitis). The programme runs the British Society of Rheumatology (BSR) Biologics Registers in Ankylosing Spondylitis (BSRBR-AS) and Psoriatic Arthritis (BSR-PsA). He is a senior investigator within the Arthritis Research UK/Medical Research Council Centre for Musculoskeletal Health and Work (with University of Southampton). Professor Macfarlane is a Chartered Statistician of the Royal Statistical Society as well as a Fellow of the Faculty of Public Health Medicine.
Professor Gary J. Macfarlane
Ólöf Anna Steingrímsdóttir received her PhD in health sciences in 2005. She is currently a senior researcher at the Department of Chronic Diseases and Aging, Norwegian Institute of Public Health. Her main expertise is within the fields of pain research, physical activity and social inequalities. She is one of three board members of the Tromsø Pain Study, and the PI of two projects on physical activity and pain, using longitudinal data from the study. Major areas of interest also include research methodology.
Ólöf Anna Steingrímsdóttir
Sara Hallberg is a health economist at Quantify Research, a Swedish consultancy specialized in health economic and epidemiologic research. She has conducted several retrospective register studies on mainly cardiovascular disease and chronic pain from a national and a pan-Nordic perspective. Consequently, she has gained an understanding of the capabilities, limitations and processes of national and regional data within the Nordic countries and acquired insight into the opportunities and challenges for accessing and pooling Nordic healthcare register data. Her research on chronic pain involves healthcare resource utilization and patient-reported outcomes. Sara holds a MSc in Economics from Stockholm School of Economics, Sweden.
Dagfinn Matre is a research professor at the National Institute of Occupational Heath in Oslo, Norway. His research focuses on understanding pain mechanisms in an occupational health perspective. Methodology includes experimental pain models and field studies assessing pain complaints in workers. His current project focuses on shift work, sleep and pain. The aim is to determine whether shift work and adverse working hours increase pain sensitivity through sleep disturbances.
Dr. Camilla I Svensson received her Ph.D. in Molecular Pathology in 2005 from University of California, San Diego (UCSD) on work focused on spinal mechanisms of pain transmission. She undertook post-doctoral work centered on inhibitory regulation of intracellular signaling in rheumatoid arthritis at the Department of Medicine, Division of Rheumatology at UCSD. Dr. Svensson was recruited to the Karolinska Institutet, Department of Physiology and Pharmacology in Stockholm in 2008, where she today is Professor of cellular and molecular pain physiology. She leads a research team exploring pain mechanisms in rheumatic disease, focusing on the role of autoantibodies and associated inflammatory and non-inflammatory processes in persistent pain. She is specifically interested in the effect these have on bone cells and glial cells in the communication with the sensory nervous system. Dr. Svensson is funded by the Swedish Research Council, the European Commission and the Family Lundblad foundation and she has received several prestigious awards including the Wallenberg Academy Award and the Ragnar Söderberg Award in Medicine.
Camilla I Svensson
Per Hansson, MD, DMSci, DDS,is a senior consultant, specialist in neurology and pain medicine at the Dept. of Pain Management and Research, Oslo University Hospital, Oslo, Norway and aprofessor of clinical pain research at Dept. of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. He received his dental and medical degrees from the Karolinska Institutet in 1979 and 1986, respectively, and his PhD in physiology at the same institute in 1985. He was appointed associate professor of physiology in 1991 and professor of clinical pain research in 2000.
Peripheral and central neuropathic pain, somatosensory testing, endogenous pain controlling systems and functional brain imaging represent major areas of interest in Professor Hansson’s research.
Professor Hansson is a reviewer for many scientific journals and has served as co-editor of Pain Reviews, on the editorial board of Pain, Clinical Updatesand as field editor for clinical medicine/neurology of the European Journal of Pain. He has published more than 180 journal articles, position papers, reviews and book chapters, and has lectured at numerous conferences and symposia worldwide. He is co-editor of 2 books published by the IASP Press.
From 2003-2006 he was president of the Scandinavian Association for the Study of Pain. He served as Honorary Secretary of the European Federation of IASP Chapters from 2008-2011. He has served as external reviewer for the German Network on Neuropathic Pain, INSERM and the Wellcome Foundation sponsored London Pain Consortium.
I have been involved in research into chronic pain at King’s for the past 15 years. I am clinically active as a consultant rheumatologist in London. My work with the bioresource TwinsUK is funded through a variety of sources including Wellcome Trust, MRC, EU and Versus Arthritis. Twin and family studies have demonstrated that chronic widespread pain (CWP) and the chronic pain syndromes are heritable. In addition, the chronic pain syndromes appear to share genetic factors. Progress at identifying the genetic factors involved has been slow but the new technologies are allowing relatively rapid advances through agnostic studies. My group has been working on a variety of omic measures – DNA methylation, epigenetics, glycans and the microbiome - to try and identify the pathologic mechanisms leading to the chronic pain syndromes.
Frances MK Williams
Nina has worked in science communication for the last twenty years – at the Research Council of Norway and in the independent online news service forskning.no and ScienceNordic.com. She has published two books, Why do we never see baby pigeons? and Science Journalism. An introduction [both in Norwegian]. She teaches science communication at universities and in forskning.no-courses. Her background is in Media Studies.
Siri Leknes is a professor of Social and Affective Neuroscience at the Department of Psychology, University of Oslo. Her PhD on Pain, reward and relief at the University in Oxford in 2008 was supervised by Professor Irene Tracey. After postdoctoral work in Gothenburg and Oslo, she established the Leknes Affective Brain (LAB) lab. The specific research questions addressed in LAB lab projects range from pain to emotion perception to neuroendocrinology and visual attention. The overarching question is: How do the brain and the body give rise to feelings that humans can perceive, and how are these feelings connected to our choices and behaviour.
MD, PhD is currently Professor of Pain Medicine at the University of Helsinki and Visiting Professor at the Karolinska Institute. She was the founding president of the Finnish Association for the Study of Pain and a former president of IASP (2010-2012). She has too many interests in the field of pain research, e.g. pharmacology of opioids, transition from acute to chronic pain, the intersection of psyche and soma in pain, evidence-based medicine, mechanisms of neuropathic pain and the role of sleep in pain. She has recently joined the new research programme SLEEPWELL at the University of Helsinki. Thanks to excellent collaborators she has been able to dive into the world of big data and machine learning. She is also proud of the Pain Management Hub currently being built to the National Virtual Hospital at the Helsinki University Hospital.
Ilangko Balasingham received the M.Sc. and Ph.D. degrees from the Department of Electronic Systems, Norwegian University of Science and Technology (NTNU), Trondheim in 1993 and 1998, respectively, both in signal processing. He performed his Master’s degree thesis at the Department of Electrical and Computer Engineering, University of California Santa Barbara, USA. From 1998 to 2002, he worked as Research Engineer developing image and video streaming solutions for mobile handheld devices at Fast Search & Transfer ASA, Oslo, which is now part of Microsoft Inc. Since 2002 he has been with the Intervention Center, Oslo University Hospital, where he heads the Section for Medical ICT R&D. He was appointed Professor of Medical Signal Processing and Communications at NTNU in 2006. For the academic year 2016/2017 he was Professor by courtesy at the Frontier Institute, Nagoya Institute of Technology in Japan. His research interests include super robust short range communications for both in-body and on-body sensors, body area sensor network, microwave short range sensing of vital signs, short range localization and tracking mobile sensors, and nanoscale communication networks. He has authored or co-authored over 240journal and full conference papers, 7 book chapters, 42 abstracts, 6 patents, and 20 articles in popular press. Ilangko has given 16 invited/ keynotes at the international conferences. In addition he is active in organizing conferences (Steering Committee Member of ACM NANOCOM 2018-2021; General Chair: the 2019 IEEE Int. Symposium of Medical ICT, the 2012 Body Area Networks (BODYNETS) conference; TPC Chair of the 2015 ACM NANOCOM) and editorial board (Area Editor of Elsevier Nano Communication Networks 2013-unti now).
University of Oslo (UiO) and National Institute of Occupational Health(NIOH), Norway
Johannes Gjerstad is Professor of Physiology at University of Oslo (UiO) and a Lead Research Professor at National Institute of Occupational Health(NIOH), Norway.In his research Gjerstad focuses on social stress and neuronal mechanisms underlyingchronic pain.Better understanding of the mechanisms underlying such neurobiological features may be important for future management of anxiety, depression and persistent pain.